McClung, M. R., Geusens, P., Miller, P. D., Zippel, H., Bensen, W. G., Roux, C., Adami, S., Fogelman, I., Diamond, T., Eastell, R., Meunier, P. J., and Reginster, J. Y. 2010;21(2):49-55. Strontium is considered to be safe in normal food amounts and as a toothpaste ingredient. Osteoporosis Int. Zinner, D. D., Duany, L. F., and Lutz, H. J. View abstract. Kanis, J. Initially Forteo was top contender (refrigeration requirement is an issue) until I came across Tymlos (refrigeration being easier to manage is one of several benefits over Forteo). This could cause the body to have too much strontium and potentially cause side effects. A. What Is Secondary Prevention of Osteoporosis? Its also referred to as being a soft metal like lead. View abstract. Bingham, C. O., III, Buckland-Wright, J. C., Garnero, P., Cohen, S. B., Dougados, M., Adami, S., Clauw, D. J., Spector, T. D., Pelletier, J. P., Raynauld, J. P., Strand, V., Simon, L. S., Meyer, J. M., Cline, G. A., and Beary, J. F. Risedronate decreases biochemical markers of cartilage degradation but does not decrease symptoms or slow radiographic progression in patients with medial compartment osteoarthritis of the knee: results of the two-year multinational knee osteoarthritis structural arthritis study. Its also not for people who: National Osteoporosis Foundation Clinical Updates: "Over-the-Counter Products & Osteoporosis: Case Discussions. Its been compared to calcium in its bone-boosting abilities. J Bone Miner Res 1999;14:1789-95. Henrotin Y, Labasse A, Zheng SX, et al. Further research is still needed and it can be dangerous to use these supplements if you have certain health conditions. View abstract. Scand J Rheumatol 2001;30(4):242-247. Loutit, J. F. Diurnal variation in urinary excretion of calcium and strontium. The disease often progresses without any symptoms or pain, and is not found until bones fracture. Strontium can attach to some antibiotics called tetracyclines in the stomach. View abstract. This article is based on scientific evidence, written by experts and fact checked by our trained editorial staff. Brand: Algaecal. View abstract. View abstract. No difference in intestinal strontium absorption after an oral or an intravenous 1,25(OH)2D3 bolus in normal subjects. I just read this article about strontium. Gillam, D. G., Newman, H. N., Davies, E. H., and Bulman, J. S. Clinical efficacy of a low abrasive dentifrice for the relief of cervical dentinal hypersensitivity. In your diet, you get it mainly from seafood, but you can also get small amounts of it in whole milk, wheat bran, meat, poultry, and root vegetables. Osteoporosis Int. Hahn, G. S. Strontium is a potent and selective inhibitor of sensory irritation. Gutteridge DH, Robinson CJ, Joplin GF. Most people who take strontium citrate report their fractures STOP. Recker R, Stakkestad J Weber T et al. Osteoporos.Int. It boils at 2,520 degrees F (1,382 degrees C) and melts at1,431 degrees F (777 degrees C). are clickable links to medically peer-reviewed studies. Am J Med 1993;95:69S-74S. Its also used to create that alerting red color in emergency flares. Baziotis N, Yakoumakis E, Zissimopoulos A, et al. View abstract. Arthritis Res.Ther. Do not take it within 2 hours of ingesting calcium so I take it at bedtime. Osteoporos.Int. Kidney Int 1999;56:1886-92. 2008;80(5):47-52. am in the same situation, I wish someone from mayo could give a good answer to us. Busse, B., Jobke, B., Hahn, M., Priemel, M., Niecke, M., Seitz, S., Zustin, J., Semler, J., and Amling, M. Effects of strontium ranelate administration on bisphosphonate-altered hydroxyapatite: Matrix incorporation of strontium is accompanied by changes in mineralization and microstructure. If you want to take a strontium supplement, ask your doctor first. J.Bone Miner.Res. View abstract. Do not be misled by marketing materials that compare them to strontium ranelate. Proc.R.Soc.Lond B Biol.Sci. Am on third brand of Strontium Citrate and doing better than on the first two. It does not recommend it as a treatment for anyonewho has or has had heart or circulatory problems such as stroke, heart attack, or obstruction of the blood flow in the arteries. (10), Radioactive strontium-89 is given intravenously for advanced bone cancer or cancer that has spread to the bones such as metastatic prostrate cancer. Scientific studies have shown that Sr may have positive effects on bone diseases like osteoporosis, bone cancer, prostate cancer, tooth sensitivity and tooth decay. It's not known if strontium contained in dietary supplements has these effects. It is said to have first been found in the ores of lead mines in Strontian in 1787. Robinson RG, Preston DF, Schiefelbein M, Baxter KG. My fear is the cost. To measure the effectiveness of it, researchers measured bone mineral density in the neck, spine and hip as well as some biochemical bone markers. (23), In general, taking very high doses of a Sr supplement is typically not considered safe and taking too much could even damage bones, so be careful when taking strontium, as recommended by the ATSDR (Agency for Toxic Substances and Disease Registry). Cochrane.Database.Syst.Rev. Best Joint Supplements In 2023: Knee Pain & Joint Support. Expert.Opin.Pharmacother. View abstract. J.Dent.Res. Towheed TE, Maxwell L, Anastassiades TP, et al. Taking strontium with quinolones might decrease their effectiveness. A number of studies have shown that it can strengthen bone and reduce the risk of fractures, even among women 74 years of age or older when risks are highest. Therapeutic Research Faculty 2020. View abstract. Bellamy, N., Campbell, J., Robinson, V., Gee, T., Bourne, R., and Wells, G. Viscosupplementation for the treatment of osteoarthritis of the knee. D'Haese, P. C., Schrooten, I., Goodman, W. G., Cabrera, W. E., Lamberts, L. V., Elseviers, M. M., Couttenye, M. M., and De Broe, M. E. Increased bone strontium levels in hemodialysis patients with osteomalacia. WebMD does not provide medical advice, diagnosis or treatment. . In addition, strontium ranelate isstopped if a patient develops heart or circulatory problems during the course of treatment. (4a) In addition, strontianite is a mineral that comes from concentrations of strontium compounds, and there are several strontium compounds. Research shows that a special prescription form of strontium (strontium-89 chloride) given intravenously (by IV) reduces pain from metastatic, Weak and brittle bones (osteoporosis). View abstract. Arthritis Rheum 1998;41:81-91. 2013 Feb;72(2):179-86. doi: 10.1136/annrheumdis-2012-202231. 1992;63(1):7-12. El-Hajj Fuleihan G. Strontium ranelate--a novel therapy for osteoporosis or a permutation of the same? Does anyone take Forteo ? Ann Rheum Dis. 2-1-2001;344(5):333-340. 2008;67(12):1736-1738. ", Beth Israel Deaconess Medical Center: "Strontium. Feeling slightly more pain in the areas of cancer in your bones for a few days. View abstract. 2005;7(3):R625-R633. @faith123, recently posted about having a second reclast infusion recently here, https://connect.mayoclinic.org/discussion/reclast-infusion/. View abstract. 5-3-2007;356(18):1809-1822. Bone 2009;45(2):200-206. N.Engl.J.Med. Gunawardana DH, Lichtenstein M, Better N, Rosenthal M. Results of strontium-89 therapy in patients with prostate cancer resistant to chemotherapy. Cochrane.Database.Syst.Rev. Kidney Int 2000;58:981-8. Quintessence.Int. Reginster, J. Y. and Meunier, P. J. Strontium ranelate phase 2 dose-ranging studies: PREVOS and STRATOS studies. 2006;3:CD005326. View abstract. Spets-Happonen, S., Seppa, L., Korhonen, A., and Alakuijala, P. Accumulation of strontium and fluoride in approximal dental plaque and changes in plaque microflora after rinsing with chlorhexidine-fluoride-strontium solution. Calcium and strontium metabolic studies in patients on CAPD. Strontium 89 in the treatment of pain due to diffuse osseous metastases: a university hospital experience. 1967;5(6):318-321. Gillam, D. G., Bulman, J. S., Jackson, R. J., and Newman, H. N. Comparison of 2 desensitizing dentifrices with a commercially available fluoride dentifrice in alleviating cervical dentine sensitivity. View abstract. View abstract. I. Inhibition of intestinal calcium absorption and 1,25-dihydroxycholecalciferol synthesis. View abstract. 2012;23(1):295-303. doi: 10.1007/s00198-011-1547-8. Strontium may also influence other essential functions, including calcium absorption, bone formation & breakdown, and it restores alkaline pH to improve the health of skin, hair, and nails). Eur.J.Endocrinol. A double-blind, randomized placebo-controlled trial published in The Journal of Clinical Endocrinology and Metabolism looked at the effects of Sr on 261 men with primary osteoporosis. 2012. Hunter House, 2014. Symptomatic efficacy of avocado/soybean unsaponifiables in the treatment of osteoarthritis of the knee and hip: a prospective, randomized, double-blind, placebo-controlled, multicenter clinical trial with a six-month treatment period and a two-month followup demonstrating a persistent effect. Eur.J.Nucl.Med. A., Korotkova, T. A., Toroptsova, N. V., Smirnov, A. V., Demin, N. V., Rodionova, S. S., Buklemeshev, IuV, and Shumskii, A. A., Mohr, D. N., Petterson, T. M., O'Fallon, W. M., and Melton, L. J., III. No tummy upset this time, have been increasing very slowly as I am very med sensitive, so was on 40mg for 10 days and now 40mg one day and 80 mg every second day for a week, but the tiredness is difficult to put up with. Mayo docs say it will stay in my system for up to three years. Strontium-89 chloride in the treatment of bone metastases from breast cancer. Seeman, E., Vellas, B., Benhamou, C., Aquino, J. P., Semler, J., Kaufman, J. M., Hoszowski, K., Varela, A. R., Fiore, C., Brixen, K., Reginster, J. Y., and Boonen, S. Strontium ranelate reduces the risk of vertebral and nonvertebral fractures in women eighty years of age and older. It also appears that people with strontium in their local water supply seem to have decreased cavity risk. This article will be helpful to you if you experience joint discomfort, especially from rheumatoid arthritis and other joint health disorders. The forms of strontium available over-the-counter in the U.S. or on the Internet are usually strontium citrate or strontium chloride. Get answers to some of the most common questions about osteoporosis treatment. Doggrell, S. A. While it may seem intimidating at first, counting macros is a common Erythritol is now one of the most popular natural zero-calorie sweeteners available. More Information (12). A., Cosman, F., Lakatos, P., Leung, P. C., Man, Z., Mautalen, C., Mesenbrink, P., Hu, H., Caminis, J., Tong, K., Rosario-Jansen, T., Krasnow, J., Hue, T. F., Sellmeyer, D., Eriksen, E. F., and Cummings, S. R. Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis. Although many people have never heard of it before, its a very interesting and somewhat controversial supplement. Health Phys 2004;86:193-6. Interested in more discussions like this? Diagnosis and Management. They can decrease strontium absorption. J Endod 2002;28:34-5. 1998-2023 Mayo Foundation for Medical Education and Research. View abstract. Quintessence.Int. Boivin, G., Farlay, D., Khebbab, M. T., Jaurand, X., Delmas, P. D., and Meunier, P. J. Neer, R. M., Arnaud, C. D., Zanchetta, J. R., Prince, R., Gaich, G. A., Reginster, J. Y., Hodsman, A. Barenholdt, O., Kolthoff, N., and Nielsen, S. P. Effect of long-term treatment with strontium ranelate on bone strontium content. View abstract. Gedalia, I., Brayer, L., Kalter, N., Richter, M., and Stabholz, A. However, supplementation with strontium has not yet been studied as tooth decay prevention. 1977;95(5):982-985. Expert.Opin.Investig.Drugs 2004;13(7):857-864. View abstract. Int.J.Rad.Appl.Instrum.B 1987;14(3):219-222. Medina, J. M., Thomas, A., and Denegar, C. R. Knee osteoarthritis: should your patient opt for hyaluronic acid injection? Available at: www.emea.eu.int/humandocs/Humans/EPAR/protelos/protelos.htm. J.Clin.Endocrinol.Metab 2005;90(5):2816-2822. According to Wikipedia, Strontianite(SrCO3) is an important raw material for the extraction ofstrontium. Cochrane.Database.Syst.Rev. Collins, J. F. and Perkins, L. Clinical evaluation of the effectiveness of three dentifrices in relieving dentin sensitivity. Skoryna SC. View abstract. 2006;34(8):608-613. View abstract. Olson, B. L., McDonald, J. L., Jr., and Stookey, G. K. The effect of strontium and fluoride upon in vitro plaque and rat caries. Acta Biomater. Oosterhof GO, Roberts JT, de Reijke TM, et al. The possible risks of strontium warrant more long-term independent studies. View abstract. The product can increase bone density, and it can also slow down bone loss. If you want to take a strontium supplement, it is recommended to ask your doctor first. Calcium Citrate. The next big and interesting use of this alkaline earth metal was when it was used in the television production industry, specifically in the cathode ray tubes of color televisions. Dent.Clin.North Am. Aging Clin.Exp.Res. Strontium citrate and strontium chloride are supplements and are not tested or regulated by the Food and Drug Administrations (FDA). 2005 - 2023 WebMD LLC. Strontium Ranelate returns to the UK as an osteoporosis drug treatment. 2019https://theros.org.uk/latest-news/2019-01-14-strontium-ranelate-returns-to-the-uk-as-an-osteoporosis-drug-treatment. You may be surprised, but strontium chloride hexahydrate is added to toothpaste to reduce the pain associated with sensitive teeth. Available at: www.servier.com/pro/osteoporose/protelos/protelos_spc.asp. Its a fancy word for the development of cavities! Ann Rheum Dis. Bone metastases can be extremely painful. Prostate cancer. Overview. Reginster, J., Minne, H. W., Sorensen, O. H., Hooper, M., Roux, C., Brandi, M. L., Lund, B., Ethgen, D., Pack, S., Roumagnac, I., and Eastell, R. Randomized trial of the effects of risedronate on vertebral fractures in women with established postmenopausal osteoporosis. View abstract. View abstract. It may even cause constipation or digestive discomfort. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. View abstract. View abstract. AlgaeCal Plus is a plant-based calcium supplement that contains all 13 bone-supporting minerals and is clinically supported to increase bone density. Bone. Osteoporos.Int. Available at: https://www.guildlink.com.au/gc/ws/servier/pi.cfm?product=sepproto. 2010;30(7):863-869. Reginster, J. Y., Lecart, M. P., Deroisy, R., and Lousberg, C. Strontium ranelate: a new paradigm in the treatment of osteoporosis. View abstract. Some people say this supplement improves bone health, but its important to think about its benefits and risks before you decide to take it. View abstract. View abstract. View abstract. Seeman, E., Devogelaer, J. P., Lorenc, R., Spector, T., Brixen, K., Balogh, A., Stucki, G., and Reginster, J. Y. Strontium ranelate reduces the risk of vertebral fractures in patients with osteopenia. April 2004. Sr should be used with caution for those with kidney disease and if you have advanced kidney disease, then strontium ranelate is not recommended at all. Some. Meanwhile, strontium citrate features a 31% elemental strontium and only 69% citrate. The objective of this study was to determine whether strontium citrate can be used to enhance bone healing during MDO in a rabbit model. Cancer that has spread to bone and causes pain. 2011;165(3):469-476. N Engl J Med 2004;350:459-68.. View abstract. J.Periodontol. 1991;13(3):21-25. Scientists havent tested these supplements much, so theres not enough research to know if they fight osteoporosis. Some years later in 1808, it was was isolated in its metallic formusing electrolysisby Sir Humphry Davy at the Royal Institution in London. Bruyre O, Reginster JY, Bellamy N, et al. 2005;54(9):758-767. J Natl Med Assoc 2002;94:706-11. This is not the same as making new bone. View abstract. Many consumers are being lured by the advertised benefits of strontium for bone health. Stable strontiums atomic symbol is Sr, its atomic number is 38 and its atomic weight is 87.62. Calcif Tissue Int 2001;69:121-9. . 2013 Feb;98(2):592-601. doi: 10.1210/jc.2012-3048. J Am Diet Assoc 1987;87:1644-50. Previous research demonstrates that strontium ranelate can promote bone formation while decreasing vertebral and nonvertebral fracture risk in women with postmenopausal osteoporosis. 1992;19(10):737-740. Ettinger, B., Black, D. M., Mitlak, B. H., Knickerbocker, R. K., Nickelsen, T., Genant, H. K., Christiansen, C., Delmas, P. D., Zanchetta, J. R., Stakkestad, J., Gluer, C. C., Krueger, K., Cohen, F. J., Eckert, S., Ensrud, K. E., Avioli, L. V., Lips, P., and Cummings, S. R. Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial. Boron seems to affect the way the . Br.J.Clin.Pharmacol. They won't do any studies but the END OF FRACTURES SAYS IT ALL! View abstract. Both soil and seawater contain this mineral. It is also among the forms of Strontium supplements backed by studies regarding safety and efficiency. Effects of strontium ranelate and alendronate on bone microstructure in women with osteoporosis. Pearce, N. X., Addy, M., and Newcombe, R. G. Dentine hypersensitivity: a clinical trial to compare 2 strontium densensitizing toothpastes with a conventional fluoride toothpaste. J.Clin.Endocrinol.Metab 2010;95(3):1174-1181. J Can Dent Assoc 2003;69:221-6. The drug makes your bones stronger and lowers your chances of getting fractures. In Australia and some countries in Europe, a form of strontium called strontium ranelate (Osseor Protelos) is available as a prescription medication to treat and prevent osteoporosis and bone fractures. Maheu E, Mazieres B, Valat JP, et al. 2017 Aug;55(8):93-94. It's not known if strontium. JAMA 12-23-1998;280(24):2077-2082. A 2016 systematic review published in European Urology took a look at several radiopharmaceuticals including Sr-89 for reducing the malignant bone pain from prostate cancer. It is an alkaline earth metalmost similar to barium and calcium. Rizzoli, R., Laroche, M., Krieg, M. A., Frieling, I., Thomas, T., Delmas, P., and Felsenberg, D. Strontium ranelate and alendronate have differing effects on distal tibia bone microstructure in women with osteoporosis. Arch Dis Child 1996;75:524-6. Possible side effects of radioactive Sr (Metastron) as a bone cancer treatment may include: (22). View abstract. View abstract. Also, the FDA doesnt regulate supplements in the same way as prescription drugs, so it's not possible to know if if they are safe or work well or even how much of the main ingredient they contain. This decreases the amount of quinolones that can be absorbed. Dermatology 2000;200(3):244-246. View abstract. View abstract. Given that strontium test results are tied to the strontium ion, citrate is your best option to reap its bone-building benefits. Do not take it within 2 hours of ingesting calcium so I take it at bedtime. I have osteoporosis and am afraid of the treatments for it have been trying strontium citrate not sure about my decision. My teeth are really strong and it feels like my bones are too. WebMD does not provide medical advice, diagnosis or treatment. Receive updates and information about Bone Health, Our Events, and Specialty Programs each month. Selective Estrogen Receptor Modulators (SERMs), Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Smoking Pot Every Day Linked to Heart Risks, Artificial Sweetener Linked to Heart Risks, FDA Authorizes First At-Home Test for COVID and Flu, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox, Bone Mineral Density Test: What to Expect, Newer Osteoporosis Treatments Build Stronger Bones, Breakfasts for Strong Bones: 12 Foods to Boost Bone Health, Cant move very much, either for a short time, such as after surgery, or for the long term, such as because of a disability. Omdahl JL, DeLuca HF. Osteoporos.Int. Strontium biokinetics in humans: influence of alginate on the uptake of ingested strontium. A prescription form of strontiumstrontium ranelate (the ranelate salt), known as Protelos/Osseor was authorized in the European Union to treat severe osteoporosis in women who have been through the menopause and men who are at high risk of broken bones or fracture in the spine and the hip. Vertebral Efficacy With Risedronate Therapy (VERT) Study Group. 2008;83(5):308-314. Les Laboratoires Servier ceased the distribution of Protelos/Osseor in August 2017. Dermatol.Surg. Interaction of strontium and vitamin D. C R Seances Soc Biol Fil 1975;169:322-9. Adami, S. Protelos: nonvertebral and hip antifracture efficacy in postmenopausal osteoporosis. View abstract. View abstract. 2011;22(8):2347-2355. So what is it? With a few simple measures, the application of Sr-89 causes no problems. Protelos European Summary of Product Characteristics. ", UC Davis School of Medicine: "Strontium Citrate for Osteoporosis Prevention Evaluation (SCOPE). However, there has also been concern over strontium ranelates effects on heart health. Gillam, D. G., Newman, H. N., Bulman, J. S., and Davies, E. H. Dentifrice abrasivity and cervical dentinal hypersensitivity. View abstract. Various tests for tooth sensitivity by the researchers revealed that compared to the placebo, the toothpaste containing Sr decreased dentinal hypersensitivity to a significantly greater degree. Positive results were seen within two weeks and continued for the 12 week length of the study. 1996;41(6):543-549. Effects of long-term strontium ranelate treatment on vertebral fracture risk in postmenopausal women with osteoporosis. Upset stomach and diarrhea are the most common side effects of magnesium oxide. J.Periodontol. Mazor, Z., Brayer, L., Friedman, M., and Steinberg, D. Topical varnish containing strontium in a sustained-release device as treatment for dentin hypersensitivity. Over-the-counter dentifrices in the treatment of tooth hypersensitivity. Eur Urol 2003;44:519-26. Cheung, K. M., Lu, W. W., Luk, K. D., Wong, C. T., Chan, D., Shen, J. X., Qiu, G. X., Zheng, Z. M., Li, C. H., Liu, S. L., Chan, W. K., and Leong, J. C. Vertebroplasty by use of a strontium-containing bioactive bone cement. What else is it good for? Evaluation of symptomatic slow-acting drugs in osteoarthritis using the GRADE system. CMAJ. View abstract. O'Donnell, S., Cranney, A., Wells, G. A., Adachi, J. D., and Reginster, J. Y. Strontium ranelate for preventing and treating postmenopausal osteoporosis. Ann.Rheum.Dis. Strontium is a mineral found in seawater and soil. Doublier, A., Farlay, D., Khebbab, M. T., Jaurand, X., Meunier, P. J., and Boivin, G. Distribution of strontium and mineralization in iliac bone biopsies from osteoporotic women treated long-term with strontium ranelate. Richy F, Bruyere O, Ethgen O, et al. 1996;67(8):737-742. Hello @bonelady welcome to Connect. Natural strontium has a silvery white metallic color with a tint of yellow. View abstract. Effects of strontium ranelate on spinal osteoarthritis progression. The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis. View abstract. Results of Russian multicenter trial]. Trends in the incidence of deep vein thrombosis and pulmonary embolism: a 25-year population-based study. View abstract. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. All rights reserved. Addy, M., Mostafa, P., and Newcombe, R. G. Effect of plaque of five toothpastes used in the treatment of dentin hypersensitivity. Doctors can prescribe it only for postmenopausal women and for men with severe osteoporosis who cant take other drugs. (Accessed 13 March 2004). I now take 680 mg strontium citrate without side effects and the fractures have stopped. (19), If youre a fan of red fireworks, you can thank strontium (specificallygaseous strontium monochloride) for that brilliant color you see every 4th of July. As a service to our readers, American Bone Health provides access to our library of archived content. With strict editorial sourcing guidelines, we only link to academic research institutions, reputable media sites and, when research is available, medically peer-reviewed studies. The Earths crust also has Sr at an estimated average of 360 parts per million. A coordinator will follow up to see if Mayo Clinic is right for you. Membership to ConsumerLab.com is available online and provides immediate access to reviews of more than 1,000 products from over 400 brands. View abstract. Accessed May 1, 2018. Tofu, firm, made with calcium sulfate, cup 253 mg per serving. 2006;(2):CD005321. Description Pure Encapsulations' Strontium capsules provide one of the many trace minerals essential to bone health. N.Engl.J.Med. Founded in 1999, ConsumerLab.com is a leading provider of consumer information and independent evaluations of products that affect health and nutrition. 2000;75(1-3):253-263. Arch Intern Med 2003;163:1514-22. "Hello @bonelady. Kaufman JM, Audran M, Bianchi G, et al. It's also known to increase osteoprotegerin that serves as the decoy for the RANKL and slows the rate of bone resorption. Lets talk about these answers and more. N Engl J Med 2004;350:504-6. 1972;43(6):367-372. Vlad, S. C., LaValley, M. P., McAlindon, T. E., and Felson, D. T. Glucosamine for pain in osteoarthritis: why do trial results differ? Rev Rhum Engl Ed 1997;64(12):825-834. Hello @bonelady. Consensus-based recommendations for the diagnosis and management of dentin hypersensitivity. View abstract. Molybdenum, nickel, cobalt, vanadium, and strontium in total diets. What you need to know about strontium suppements for osteoporosis. The compound Strontium Citrate has CAS number 40182-75- and molecular formula C6H5O7Sr-. Strontium ranelate increases cartilage matrix formation. Methods: Custom-made MDO devices were placed on 20 New Zealand White rabbits. View abstract. View abstract. Even though its not considered a nutrient, its known that the human body can absorb strontium and utilize it as it would calcium. Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. Lancet 12-7-1996;348(9041):1535-1541. This information may not fit your specific health circumstances. 2008;58(6):1687-1695. View abstract. Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators. Black, D. M., Cummings, S. R., Karpf, D. B., Cauley, J. Strontium is a mineral and alkaline earth metal like calcium, and it seems to work similarly to calcium in the body with its main benefit being a boost to bone health. View abstract. Rintelen, B., Neumann, K., and Leeb, B. F. A meta-analysis of controlled clinical studies with diacerein in the treatment of osteoarthritis. Overall, the results of this 2013 study performed with male subjects demonstrated that strontium ranelate supplementation appears to improve bone mineral density in men similar to the way it has been shown to help postmenopausal women struggling with osteoporosis. Roque, I. Figuls, Martinez-Zapata, M. J., Scott-Brown, M., and Alonso-Coello, P. Radioisotopes for metastatic bone pain. Reduce bone loss and build stronger muscles. Kidney Int. McAlindon TE, LaValley MP, Gulin JP, Felson DT. Theres not enough research to know if strontium fights osteoporosis. Calcif Tissue Int 2000;67:122-7. The effect of prior bisphosphonate therapy on the subsequent therapeutic effects of strontium ranelate over 2 years. 4-12-2005;172(8):1039-1043. Human biokinetics of strontium--part II: Final data evaluation of intestinal absorption and urinary excretion of strontium in human subjects after stable tracer administration. Acta Derm Venereol. Naess, I. Rozhinskaia, L. I., Arapova, S. D., Dzeranova, L. K., Molitvoslovova, N. N., Marova, E. I., Il'in, A. V., Benevolenskaia, L. I., Nikitinskaia, O. View abstract. [No authors listed]. Disease-modifying effect of strontium ranelate in a subset of patients from the Phase III knee osteoarthritis study SEKOIA using quantitative MRI: reduction in bone marrow lesions protects against cartilage loss. Kidney Int 2003;64:534-43. . 9-25-2006;166(17):1899-1906. Clin Chem 1999;45:1548-56. Because strontium and calcium have very similar molecular structures, the body treats them much the same. Have you discussed any treatments with your doctor or have they recommended anything to you? One scientific review published in 2014 by a doctor with admitted ties to pharmaceutical makers concludes, The increased risk for cardiac events with strontium ranelate has been detected in randomized clinical trials but not in real-life observational studies. (9), Ultimately, the European Union now only endorses the use of strontium ranelate in severe cases of osteoporosis with high fracture risk. Bone 2009;45(6):1059-1064. After you stop taking any of these bone-building medications, you generally will need to take another osteoporosis drug to maintain the new bone growth.